Prevalence of urinary tract infection and the validity of urine analysis in the diagnosis of uti in febrile under-fives at Nnamdi Azikiwe University Teaching Hospital, Nnewi: a cross-sectional study
Abstract
Urinary tract infection (UTI) is a common cause of fever in febrile under-fives, but this is often overlooked due to the ambiguity of its presentation, especially in this malaria-endemic region. This makes clinical recognition difficult despite the potential risk of renal scarring and chronic kidney disease (CKD) later in life, if inappropriately treated. Additionally, urine culture, the gold standard for diagnosis, is limited by its time-consuming nature. Due to the wide variation in reports on the accuracy of the dipstick test as a rapid screening test for UTI in children, studies are necessary to validate its relevance in the diagnosis of UTI in different practice localities. This study evaluated the effectiveness of dipstick urinalysis in diagnosing UTIs in febrile children under five years old at Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi. Three hundred thirty children aged 1 month to 59 months with an axillary temperature of ≥ 37.5 °C were recruited consecutively from July 2016 to April 2017 from the Children Outpatient (CHOP) and the Children Emergency Room (CHER). Sociodemographic and clinical data were collected using interviewer-administered questionnaires. Urine samples were collected from each participant for dipstick urinalysis, microscopy, and culture testing. Data were analysed using SPSS software version 21. The level of significance for tests of association was set at 5%. There were 218 males and 112 females, resulting in a male-to-female…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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