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Study Microscopic Differences in Urine Samples between Males and Females with Urinary Tract Infection: A Cross-Sectional Study

Eman K. Matshar, I. Raheem, Ban S. Atyah, Nawras Kadhim Rassin

Academic Journal of International University of Erbil, 2026

Abstract

Background: Urinalysis is an established diagnostic procedure, and multiple parameters may differ by biological characteristics and pre-analytical factors, including gender. The purpose was to detect gender differences in microscopic urinalysis observations using midpoint-based quantitative analysis. A cross-sectional comparative analysis of urine samples of men and women was performed. We performed standardized microscopic scoring and statistical comparison between sexes to evaluate red blood cells (RBC), pus cells (PUS), epithelial cells, crystals, mucus and bacterial presence. Women showed significantly higher RBC midpoint scores and bacterial detection rates compared to males. Female epithelial cell scores were also notably higher, which might be due to anatomical or sample collection–related effects. No gender differences existed in PUS, crystal or mucus scores. Gender has strong effect on particular urinalysis parameters, especially RBC counts, epithelial cells and bacterial findings. These results emphasize the relevance of gender considerations for interpreting routine urinalysis results to aid in diagnosis

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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