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Prevalence of urinary tract infections and antibiotic susceptibility patterns of bacterial isolates in first-time ANC attendees at a secondary health facility in Ghana: a cross-sectional study

K. Opare-Asamoah, E. K. Vicar, J. X. Sosu, Eunice Nyarko, Sulemana Zakariah Mustapha, K. Mumuni, N. K. Aboagye, Saeed F. Majeed et al.

BMC Pregnancy and Childbirth, 2025

200 participants · 3 citations

Abstract

Urinary tract infections (UTIs) in pregnant women are a common public health concern. Identifying the prevalence of bacteriuria, the causative organisms, and their anti-microbial susceptibility profiles against commonly prescribed antibiotics used to treat UTIs among pregnant women is an aim this study seeks to attain. This aim is critical in achieving the Sustainable Development Goals 3.1 and 3.2, targeted at reducing the scourge of global maternal mortality. This hospital-based cross-sectional study was conducted among pregnant women seeking antenatal care at a secondary health facility in Ghana. Mid-stream urine samples from the study participants were collected aseptically, and their physical and biochemical composition was determined semi-quantitatively. Urine samples were examined, and microscopy was conducted, after which they were cultured. Organisms in significant urine culture growth were isolated and tested against commonly prescribed antibiotics used to treat UTIs at the facility using standard protocols to determine their antibiotic sensitivity patterns. A total of 200 pregnant women with a mean age of 27.8 ± 6.1 years participated in the study. Almost half, 48.0% (96) of all the study participants, reported for booking in the second trimester of their pregnancy. A 39.0% (78/200) positive culture growth in all the urine samples, with bacteria species responsible for the culture growth in 21.5% (43/200) of the total urine samples, was noted in this study.…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 200 participants or records.

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