The Interrelationship Between Andropause Symptoms, Testosterone Levels, and Lower Urinary Tract Symptoms in Men With Benign Prostatic Hyperplasia (BPH): A Cross-Sectional Study
Abstract
Introduction This study aimed to assess the prevalence of andropause symptoms and testosterone levels in male patients with symptomatic benign prostatic hyperplasia (BPH), as well as to explore the relationship between these factors. Methods A total of 183 male patients aged 50 years and older with diagnosed lower urinary tract symptoms (LUTS) due to BPH were included. Andropause symptoms were evaluated using the Male Andropause Symptoms Self-Assessment Questionnaire (MASSQ), while testosterone levels were measured using a chemiluminescent immunoassay. LUTS severity was assessed through the International Prostate Symptom Score (IPSS) and erectile function via the International Index of Erectile Function-15 (IIEF-15). However, the cross-sectional design and it being conducted in a single center limit the study. Results The mean andropause symptom score was 57.24 ± 12.62, indicating moderate to severe symptoms. A significant correlation was observed between increasing lower urinary tract symptom (LUTS) severity and higher andropause symptom scores (p < 0.001). Testosterone levels were significantly lower in patients with severe LUTS (285.94 ± 106.9 ng/dL) compared to those with mild LUTS (544.09 ± 109.8 ng/dL). Additionally, comorbidities such as diabetes mellitus and hypertension were associated with increased severity of both LUTS and erectile dysfunction (ED). Conclusions The study highlights a significant prevalence of andropause symptoms in men with BPH, emphasizing the…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 183 participants or records.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.