Impact of Chronic Cocaine Use on Urinary Tract Infection Recurrence and Complications
Abstract
Urinary tract infections are a common and well-understood condition; however, their occurrence in males, particularly in the context of chronic substance use, is less well-understood. This case report focuses on a 72-year-old homeless veteran, with a history of long-term crack cocaine use and frequent urinary tract infections (UTIs) resistant to treatment. Chronic cocaine use induces a persistent inflammatory state in the body, which can promote antimicrobial resistance and increase the frequency and duration of infections such as UTIs. Complications of cocaine use, such as hyperthermia and dehydration, can lead to increased urinary concentration and stasis, which further promotes urinary complications. Although the relationship between chronic substance use and recurrent infections has not been extensively studied, psychosocial consequences produced by substance use are also a prominent factor in delayed medical treatment, contributing to recurrent infections. Additional research into the psychological and physiological effects of substance use and its link to recurrent infections, such as UTIs, may help illuminate appropriate treatment strategies for socially compromised patients.
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