Genetic and phenotypic detection of beta-lactamase isolated from Proteus mirabilis bacteria in hospitals of Anbar Province
Abstract
The study aimed to isolated Proteus mirabilis and determine the genotype and phenotype of the beta-lactamase enzymes produced by these bacteria. 242 samples were collected from various pathogenic cases during the period of August 2023 to January 2024. fifty three isolates of Proteus mirabilis were isolates Distributed as follows: 47 isolates (88.7%) were obtained from urinary tract infection, 5 isolates (9.4%) from otitis media, while one isolate (1.9%) from vaginitis . the samples were diagnosed culturally using appropriate culture media , microscopically using the Gram stain and biochemically. then the isolates were confirmed using the VITEK Compact 2 device. After confirming the isolates, a sensitivity test was conducted against some antibiotics that belong to different groups, and the results showed that the highest resistant was against the antibiotic cefotaxime with a rate of 56.6%, and Amikacin with a rate of 41.5% followed by Amoxicillin-Clavulanic acid with 35.9% , while ciprofloxacin, levofloxacin, cefepime, and azithromycin the resistant rates were moderate with percentages 30.2% , 28.3% , 26.4% , and 20.8% respectively. The lowest percentages of resistance shown by the isolates was against Azeteronam with 5.7% , and imipenem with 3.8% , while for meropenem, all isolates were sensitive to this antibiotic. The results showed that 43.4% of the isolates were Multi-Drug Resistance, as the number of isolates that have resistance to more than three of the selected…
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.