Does Cognition Status Affect Spinal Surgery Outcomes: A Systematic Review and Meta-Analysis
Abstract
BACKGROUND CONTEXT
Mild cognitive impairment (MCI) and Dementia have been shown to be independent risk factors for complications after spine surgery. To date, no systematic review has been conducted on the effect of cognitive impairment (CI) on spine surgery outcomes.
PURPOSE
This study aims to perform a systematic review and meta-analysis of previous studies on perioperative outcomes and facility-based measures in cognitively impaired patients undergoing spine surgery.
DESIGN
Systematic Review and Meta-analysis PATIENT SAMPLE: 11 articles encompassing approximately 16,070 patients with cognitive impairment were included in this study.
OUTCOMES MEASURED
Data on postoperative outcomes including delirium, urinary tract infection (UTI), myocardial infarction, pulmonary embolism (PE), deep vein thrombosis (DVT), pneumonia, surgical site infection (SSI), wound dehiscence, sepsis, acute kidney injury, reoperation, readmission, intensive care unit (ICU) admission, length of stay, and cost were collected and assessed.
METHODS
A systematic search of PubMed, Embase, Cochrane Library, and Web of Science was conducted on July 8th, 2024. This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies directly comparing spine surgery outcomes in cognitively impaired populations versus normal cognition were included for meta-analysis. A Random-effect model was used to estimate the pooled odds ratios of…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 16,070 participants or records.
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