Inhibitory Potential of Momordica Charantia Fruit Extract Against Microbial Isolates of Urinary Tract Infection
Abstract
Urinary Tract Infection (UTI) is a prevalent bacterial infection that carries serious health risks on the present global scale due to its increasing morbidity rates and antibiotic resistance. This study was designed to assess the inhibitory effect of the fruit extract of Momordica charantia (bitter gourd) on bacteria causative agents of UTIs such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa collected from UTIs patients. This study adopted an experimental research design, which involved using the Kirby-Bauer disc diffusion technique. The concentration of methanol extracts used in this study was 50%, 75%, and 100%. It was observed that there was no inhibition recorded at 50% concentration, while there was a significant zone of inhibition at both 75% and 100% concentrations (p = 0.000 < 0.05). These findings suggest that M. charantia fruit methanol extract possesses inhibitory properties and can serve as a candidate for controlling bacterial growth in UTI cases.
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