Distribution and antimicrobial susceptibility patterns of uropathogens causing urinary tract infections in the patients visiting pims islamabad
Abstract
Urinary tract infections (UTIs) pose a significant burden on healthcare systems worldwide, with a prevalence rate of 20% among patients attending Pakistan Institute of Medical Sciences (PIMS) Islamabad. This study aimed to investigate the distribution and antimicrobial susceptibility patterns of uropathogens causing UTIs among patients visiting PIMS Islamabad. A total of 180 urine samples, collected from patients presenting clinical evidence of UTIs, were analyzed over a two-month period. The majority of patients affected were females (65%) compared to males (35%), with a higher prevalence observed in the age group of 15-25 years. Escherichia coli emerged as the most prevalent uropathogen (33.88%), followed by Candida albicans (30%) and Klebsiella pneumoniae (23.33%). Gram-negative bacteria constituted 62.77% of isolates, with Gram-positive cocci accounting for 7.06%. Antimicrobial susceptibility testing revealed varying resistance patterns among uropathogens, with Penicillin exhibiting the highest resistance (100%) and Vancomycin demonstrating the highest sensitivity (100%). Notably, Amikacin and Nitrofurantoin displayed notable efficacy against E. coli. These findings underscore the importance of targeted antimicrobial therapy in UTI management. The study provides valuable insights into the epidemiology and antimicrobial resistance profile of UTIs in the region, aiding in the development of effective treatment strategies tailored to local conditions. This research…
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.