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Esophageal Hypervigilance is Prevalent across Gastroesophageal Reflux Disease Presentations

Livia Guadagnoli, Rena H. Yadlapati, T. Taft, J. Pandolfino, M. Tye, L. Keefer

Neurogastroenterology and Motility, 2021

43 citations

Abstract

There is a need to identify factors outside of abnormal reflux that contribute to gastroesophageal reflux disease (GERD). Esophageal hypervigilance is a psychological process impacting symptom experience in esophageal disease. However, little is known about the presence of hypervigilance in GERD phenotypes, especially in those with abnormal acid exposure or symptom index scores. The primary aim was to assess differences in self‐reported esophageal hypervigilance across different GERD presentations. The secondary aim was to evaluate esophageal hypervigilance as a predictor of symptom severity.

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