Confocal Endomicroscopy for Non-Erosive Reflux Disease Detection (CENERDD)
Abstract
Primary Objective:
Evaluate response to NERD treatment between patients with normal endomicroscopy findings compared with patients with abnormal endomicroscopy findings.
Secondary Objectives:
To evaluate the role of probe based endomicroscopy in the diagnosis of NERD by evaluating dilated intercellular spaces, evaluation of IPCL, and quantification of fluorescein leak.
Quality of life at study entry and end of study. Compare two medications under study within each group as a subgroup analysis.
Conditions: Non-erosive Reflux Disease, Gastroesophageal Reflux.
Primary outcome: Evaluate non erosive reflux disease (NERD) Symptoms..
Enrollment: 5 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 5 participants or records.
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