Etiology, pathophysiology and medical management of gastroesophageal reflux disease
Abstract
The symptoms of sub sternal burning and/or acid regurgitation brought on by the abnormal reflux of stomach contents into the esophagus are what define gastroesophageal reflux (GERD).Most patients with chronic heartburn will report having trouble falling asleep or staying asleep through the night due to reflux symptoms.Reflux symptoms are becoming more and more common in the developed world.The effectiveness of both LNF and CNF over ten years was found to be similar regarding the alleviation of GERD symptoms, the use of proton pump inhibitors (PPIs), quality of life improvements, and objective reflux control as demonstrated by impedance studies.Consequently, the long-term findings from this trial provide level 1 evidence supporting LNF as the preferred surgical option for GERD
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