Gastroesophageal reflux disease diagnosis and treatment
Abstract
It remains a challenge to diagnose and treat gastro-esophageal reflux (GER) and GER disease (GERD) in infants and children. Together with Embase, MEDLINE, and the Cochrane Database, the published guidelines and position papers were reviewed and summarized in order to suggest a realistic GER and GERD strategy and management for healthcare providers and to standardize and enhance the quality of care for infants and children. Two algorithms were developed for this purpose, 1 for infants <12 months of age and the other for older children. None of the signs and symptoms of GER and GERD are unique and there is no screening test or tool for a gold standard. As a first-line approach, nutritional management is recommended in babies, while for early management, a clinical trial with antacid medication is recommended in children. The aim of the realistic recommendations of this review is to optimize GER management in infants and older children and to minimize the number of investigations and the improper use of medication.
Keywords: Gastro-esophageal reflux, Gastroesophageal reflux disease, Esophagitis, Endoscopy, Impedance, Proton pump inhibitors, pH.
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