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Quality of life in total fundoplication surgery versus partial fundoplication in patients with gastroesophageal reflux disease

Eduardo Sánchez-Soriano, Itzel G. García-Félix, S. Gómez-Arenas

International Surgery Journal, 2025

35 participants

Abstract

Background: Gastroesophageal reflux disease (GERD) is a chronic disease with a prevalence of 20%, which has increased in recent years with complications such as Barrett's esophagus and risk of esophageal adenocarcinoma. Therefore, its medical and surgical treatment is crucial for the prognosis.

Methods: A retrospective cohort study of quality of life using the GERD questionnaire (GERDQ) was performed in patients with GERD who received surgical treatment with one-year postoperative follow-up at a tertiary care hospital in 2023. Patients were divided into two groups based on treatment: total fundoplication (group A) and partial fundoplication (group B). Statistical analysis included percentages, means, standard deviations, and group comparisons using the Chi-square test.

Results: Of the 35 patients, the mean age was 53.71±11.26 years, more frequent in women (54.30%). Typical symptoms were presented in 85.70% of cases, with persistence of these in 68.60%, indicating surgery, with symptoms lasting 122±68.88 days. The most frequent comorbidities were obesity and diabetes (22.90%). 54.30% underwent total fundoplication (group A) and 45.70% underwent partial fundoplication (group B). A low probability of presenting GERD after surgery was 78.90% in group A versus 75% in group B.

Conclusions: The quality of life is good in patients with GERD after surgical treatment, both with total fundoplication and partial fundoplication, obtaining a low probability of presenting GERD in both…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 35 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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