To Study the Prevalence of Asthma in Patients of Gastroesophageal Reflux Disease in Tertiary Care Centre in Western U.P
Abstract
Background: Gastroesophageal reflux disease (GERD) is a prevalent gastrointestinal disorder with significant extra-esophageal manifestations, notably asthma. The association is complex and bidirectional. Indian data, particularly from Western Uttar Pradesh, remain limited. Objectives: To determine the prevalence and severity of asthma in GERD patients and evaluate their demographic, clinical, and lifestyle profile. Methods: A cross-sectional study was conducted over 18 months at LLRM Medical College, Meerut. Fifty-eight GERD patients ( ≥15 years) underwent clinical evaluation, pulmonary function tests (PFTs), and upper GI endoscopy. Demographics, dietary/lifestyle factors, comorbidities, and laboratory parameters were assessed. Statistical analysis was performed using chi-square and t-tests; p<0.05 was considered significant. Results: The mean age was 38.2±13.2 years; males (62.1%) predominated. GERD severity distribution: mild (62.1%), moderate (25.9%), severe (12.1%). Asthma prevalence was 65.5% (mild 27.6%, moderate 22.4%, severe 15.5%). A strong positive correlation was observed between GERD and asthma severity (p<0.05). Lifestyle risk factors included spicy food intake (60.3%), late bedtime (<2 hrs post-dinner, 69%), non-vegetarian diet (58.6%), sedentary lifestyle. (46.6%), and smoking (32.8%). Hypertension (25.9%) and diabetes (10.3%) were the most frequent comorbidities. PFTs revealed a progressive decline in FEV₁ with increasing GERD severity. Conclusion: Asthma is…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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