Surgical site infection due to Mycobacterium wolinskyi after inguinal hernia surgery: A case report and review of the literature
Abstract
Mycobacterium wolinskyi (MW) is a rapidly growing mycobacterium that was first identified in 1999 using 16S rRNA gene sequencing. Although the number of reported cases of MW infection has been increasing in recent years, surgical site infections (SSIs) caused by MW remain rare, and standardized treatment regimens and durations have not yet been established. Herein, we report a case of SSI caused by MW after transabdominal preperitoneal repair intervention, along with a review of SSI cases caused by MW. An 86-year-old woman underwent transabdominal preperitoneal repair of an inguinal hernia with a synthetic mesh at another hospital. As the patient developed an SSI, drainage was performed; however, no pathogens were identified. At the the request of the patient, she was transferred to our hospital, and the infected mesh was removed. MW was isolated from the infected mesh. After completion of 24 weeks of oral minocycline and levofloxacin treatment, the patient was followed up for 1 year, and no recurrence was observed. We reviewed published cases of MW-associated SSI. All patients recieved a combination of antimicrobial therapies that involved two or more agents. Among the reported cases, fluoroquinolones were most frequently used (19 cases), followed by tetracyclines (15 cases). Our findings highlight that MW can be a potential causative organism of SSIs, particularly when routine cultures do not yield the typical pathogens. Prompt surgical intervention, including effective…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Ferulic acid regulates the AKT/GSK-3β/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model
- Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli
- Photochemical behavior of levofloxacin
- Correlation Between Dissolution Profiles of Salt-Form Drugs in Biorelevant Bicarbonate Buffer and Oral Drug Absorption: Importance of Dose/ Fluid Volume Ratio
- Evaluation of the synergistic potential and mechanisms of action for de novo designed cationic antimicrobial peptides
- Synthesis of [11C]levofloxacin
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.