Comment on “Esophageal dilatation and interstitial lung disease in systemic sclerosis: A cross-sectional study”
Abstract
Interstitial lung disease is the leading cause of death in systemic sclerosis (SSc) Despite this, many transplant programs exclude SSc patients from transplantation consideration due to concern for gastroesophageal reflux induced pulmonary injury via esophageal dysfunction Recent studies that examined lung transplantation outcomes in SSc patients do not support this categorical exclusion [2]. We investigated the esophageal diameter on high-resolution computed tomography (HRCT) of the thorax that is associated with ILD in patients with SSc. esophageal
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Evidence Hub reads this as a cross-sectional. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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