IDDF2019-ABS-0085 The yield of combined multichannel intraluminal impedance and PH monitoring (MII-pH monitoring) among patients with suspected refractory gastroesophageal reflux disease: a six-year experience in a multicenter, tertiary level hospitals in the philippines
Abstract
Background Multichannel intraluminal impedance used in combination with pH-metry (MII-pH) has been shown to allow accurate recording of gastroesophageal reflux at all pH levels. In the Philippines, there is no local data on the yield of these tests in the investigation of the patients with suspected refractory GERD as well as on the phenotypic profiles of Filipino patients being referred for esophageal reflux monitoring. The main objective of the study is to determine the yield of combined multichannel intraluminal impedance and pH monitoring among patients with suspected refractory GERD at St. Luke’s Medical Center, Quezon City and Global City. Study design Retrospective, Cross-sectional, Chart Review. Participants Suspected Refractory GERD patients who underwent MII-pH. Statistical analysis Descriptive statistics. Results There is a total of 150 subjects included in the study. Majority of the patients was in their 4th to 5th decade of life, presented with typical symptoms of reflux, specifically heartburn (44.00%) and regurgitation (40.00%). In terms of EGD findings, 52.00% of patients have no signs of esophagitis. The manometric findings most commonly revealed normal esophageal motor function (52.00%). It can be noted that patients with phenotypic group of persistent acid reflux, revealed an overall prevalence of 20.00%. Around 40.00% of patients presented with esophagitis on EGD, alongside with normal manometric findings (60%), and positive SI (60.00%)/positive SAP…
Read the paper
Related studies
- Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use
- Ivth brazilian consensus conference on helicobacter pylori infection
- A pSMAD/CDX2 complex is essential for the intestinalization of epithelial metaplasia
- S2k-Leitlinie Gastroösophageale Refluxkrankheit und eosinophile Ösophagitis der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – März 2023 – AWMF-Registernummer: 021–013
- Step-by-step management of refractory gastresophageal reflux disease
- Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger–Ellison Syndrome
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.