Endoscopic assessment of gastroesophageal reflux disease patients and risk factors of esophageal lesions
Abstract
Background: Gastro-esophageal reflux disease (GERD) is a common esophageal disorder in Bangladesh. GERD is associated with significant impaired quality of life and sometimes complicated with high morbidity and mortality. Objective: To investigate upper Gl endoscopic findings in patients having typical symptoms of GERD and the risk factors of esophageal lesions in GERD patients. Methods: This was a cross-sectional descriptive type of study conducted at a private clinic in Rajshahi city. All the adults attending at the clinic having typical GERD symptoms more than 6 weeks constituted the study population. Total 108 GERD patients were included in this study. Data were collected by a data collection sheet through interview and patient examination including UGI endoscopy. Chi-square test was applied to find out the association between Clinico-demographic characteristics and GERD status of the study subjects. Multiple logistic regression analysis was done to identify the risk factors to develop esophageal lesion in GERD patients. Results: A total of 108 GERD patients, 88 (81.5%) were nonerosive reflux disease (NERD) patients and the rest 20 (18.5%) patients had esophageal lesions. Of those 20 GERD patients with esophageal lesion, 9 (8.3%) had erythema, 5 (4.6%) had erosion, 4 (3.6%) had hiatus hernia with esophagitis and only 2 (1.8%) had Barretts. Twenty-four (22.2%) patients had endoscopic evidence of gastroduodenal lesions. Older age and diabetes mellitus were identified as…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 108 participants or records.
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