Squamous Papilloma of the Esophagus in a Patient With Refractory Gastroesophageal Reflux Disease
Abstract
We report a case of a 35-year-old woman with persistent gastroesophageal reflux disease (GERD) despite lifestyle modification and medical therapy. Endoscopy revealed a squamous papilloma in the distal esophagus, a rare benign lesion linked to chronic mucosal irritation. The lesion was excised, and histopathology confirmed squamous papilloma without dysplasia. This case underscores the importance of endoscopic evaluation in patients with uncontrolled reflux and highlights the potential link between GERD and benign esophageal neoplasms.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use
- Ivth brazilian consensus conference on helicobacter pylori infection
- A pSMAD/CDX2 complex is essential for the intestinalization of epithelial metaplasia
- S2k-Leitlinie Gastroösophageale Refluxkrankheit und eosinophile Ösophagitis der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – März 2023 – AWMF-Registernummer: 021–013
- Step-by-step management of refractory gastresophageal reflux disease
- Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger–Ellison Syndrome
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.