Lymphocytic Esophagitis Mimicking Allergic Esophagitis: A Case Report
Abstract
Lymphocytic esophagitis (LE) is a rare inflammatory condition of the esophagus, characterized by intraepithelial lymphocytic infiltration of the esophageal mucosa. Despite its increasing recognition recently, standardized guidelines for diagnosis and management are still lacking. LE is frequently associated with conditions that alter esophageal pH, including gastroesophageal reflux disease (GERD), Crohn's disease, and diabetes mellitus. This report describes a 55-year-old male who presented with dysphagia and intermittent heartburn. Esophagogastroduodenoscopy (EGD) revealed LE along with incidental Helicobacter pylori gastritis. Management typically focuses on addressing underlying conditions, with proton pump inhibitors (PPIs) and topical steroids being the most common therapeutic approaches. The discussion highlights the prevalence, diagnostic challenges, and treatment strategies for LE.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use
- Ivth brazilian consensus conference on helicobacter pylori infection
- A pSMAD/CDX2 complex is essential for the intestinalization of epithelial metaplasia
- S2k-Leitlinie Gastroösophageale Refluxkrankheit und eosinophile Ösophagitis der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – März 2023 – AWMF-Registernummer: 021–013
- Step-by-step management of refractory gastresophageal reflux disease
- Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger–Ellison Syndrome
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.