Clinical course features of NON-erosive gastroesophageal reflux disease in school-aged children
Abstract
Introduction. The progression of gastroesophageal reflux disease (GERD) in children without accompanying conditions like neurological deficits or congenital esophageal anomalies remains uncertain. It is unclear whether GERD advances during childhood or predisposes individuals to GERD in adulthood. Objectives. Assess the clinical course characteristics of non-erosive GERD in school-age children. Methods. A retrospective study was conducted involving 31 children aged between 7 to 17 years, with an average age of 12.7±1.9 years. Among them, 19 were girls and 12 were boys, all diagnosed with non-erosive gastroesophageal reflux disease (GERD). The main inclusion criteria for the study were the presence of regular heartburn occurring at least once a week and the absence of erosive changes in the esophagus as confirmed by fibrogastroduodenoscopy. Follow-up examinations were performed at intervals of 6-12 months, 12-24 months, and beyond 24 months, during which the clinical symptoms and esophageal condition were monitored using fibrogastroduodenoscopy. Results. Non-erosive GERD was more prevalent in girls, accounting for 19 out of 31 cases (61.2%), predominantly among high school-aged individuals. The average age of disease onset was 12.7±1.9 years. The clinical presentation of non-erosive GERD predominantly featured symptoms such as heartburn (100.0%), abdominal pain (96.7%), nausea (45.1%), and belching (45.1%). Additionally, 22.6% of patients exhibited symptoms overlapping with…
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