Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis
Abstract
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. This study will evaluate the effectiveness of sildenafil, a medication that increases blood flow to the lungs, at improving breathing function, exercise capacity, and quality of life in people with advanced IPF.
Conditions: Pulmonary Fibrosis, Hypertension, Pulmonary.
Primary outcome: Change in 6-minute Walk Distance From Enrollment to Week 12 (≥ 20% Improvement).
Enrollment: 180 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 180 participants or records.
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