Androgen Modulation of Response to Selective Phosphodiesterase Inhibitors in Erectile Dysfunction
Abstract
The purpose of this placebo-controlled study is to determine if testosterone replacement therapy, administered by transdermal gel, can improve the response to sildenafil (Viagra R) treatment in men who have erectile dysfunction (ED) and low testosterone levels.
Conditions: Erectile Dysfunction, Testosterone Deficiency, Diabetes.
Primary outcome: Change From Baseline in Erectile Function Domain Score of the International Index of Erectile Function (IIEF).
Enrollment: 140 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 140 participants or records.
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