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Sildenafil citrate efficacy 8 h postdose in men with mild to moderate erectile dysfunction

McCullough AR, Steidle CP, Kaufman J, Goldfischer ER, Klee B, Carlsson M

International journal of impotence research, 2008

601 participants · 5 citations

Abstract

In two randomized, double-blind, placebo-controlled trials of 100 mg sildenafil citrate, men (N=601) with mild to moderate erectile dysfunction (ED) attempted intercourse 8 h (range, 7-9 h) postdose. The baseline to end-of-treatment improvement in the sildenafil groups vs placebo was greater (P50). Thus, responsiveness to 100 mg sildenafil may persist for 8 h postdose in men with mild to moderate ED.

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 601 participants or records.

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