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Efficacy of Maternal Influenza Vaccination Against All-Cause Lower Respiratory Tract Infection Hospitalizations in Young Infants: Results From a Randomized Controlled Trial

M. Nunes, C. Cutland, Stephanie A. Jones, S. Downs, A. Weinberg, J. Ortiz, K. Neuzil, E. Simőes et al.

Clinical Infectious Diseases, 2017

74 citations

Abstract

Summary Influenza vaccination during pregnancy decreased the incidence of acute lower respiratory tract infection hospitalizations in infants born to vaccinated mothers. The benefits of protecting against influenza virus infection during early infancy might extend beyond protecting only against influenza-confirmed illness.

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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