Eating Disorders in the Context of Gastrointestinal Diseases—A Narrative Review
Abstract
Background/Objectives: The clinical overlap between gastrointestinal (GI) conditions and psychiatric disorders represents a challenge in clinical practice. Eating disorders (EDs), including anorexia nervosa, bulimia nervosa, binge eating disorder (BED), and avoidant/restrictive food intake disorder (ARFID), may co-occur with gastrointestinal (GI) diseases and complicate their management. Orthorexia nervosa is a proposed and emerging construct characterized by pathological preoccupation with healthy eating and rigid dietary practices. This narrative review aims to summarize current evidence regarding eating disorder symptomatology, ARFID screening and diagnosis, orthorexic symptomatology, pathophysiological mechanisms, and diagnostic challenges across gastrointestinal diseases, with particular attention to inflammatory bowel disease (IBD), disorders of gut-brain interaction (DGBIs), celiac disease, eosinophilic esophagitis, upper gastrointestinal motility disorders, and the potential role of the gut microbiota. Methods: The review was structured in accordance with the SANRA guidelines. A structured literature search was conducted primarily in PubMed, with Scopus and Google Scholar used as supplementary sources for identifying additional relevant publications through citation tracking and examination of reference networks, for articles published from 2011 through early 2026. Results: The available literature indicates an association between GI disorders and disordered eating,…
Read the paper
Related studies
- The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices
- The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities
- In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling
- In silico prediction of splice-altering single nucleotide variants in the human genome
- In silico clinical trials: how computer simulation will transform the biomedical industry
- In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.