Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in Emergency Departments in Pakistan
Abstract
The primary objective is to determine if the administration of a single dose of oral ondansetron (an anti-vomiting medication), compared to placebo, results in a reduction in intravenous (IV) rehydration therapy in children presenting for emergency department care with some dehydration, vomiting and diarrhea in Pakistan.
SOME Dehydration is defined as 2 or more of the following signs and symptoms:
* Restlessness, irritability
* Sunken Eyes
* Drinks eagerly, thirsty
* Skin pinch goes back slowly
Conditions: Dehydration, Gastroenteritis, Vomiting, Diarrhea.
Primary outcome: Intravenous (IV) Rehydration.
Enrollment: 918 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 918 participants or records.
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