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Concentration‐dependent clinical and prognostic importance of high‐sensitivity cardiac troponin T in heart failure and a reduced ejection fraction and the influence of empagliflozin: the EMPEROR‐Reduced trial

M. Packer, J. Januzzi, J. Ferreira, S. Anker, J. Butler, G. Filippatos, S. Pocock, M. Brueckmann et al.

European Journal of Heart Failure, 2021

39 citations

Abstract

Circulating troponin is an important measure of risk in patients with heart failure, but it has not been used to determine if disease severity influences the responses to drug treatments in randomized controlled trials.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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