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Personalizing eating disorder treatment using idiographic models: An open series trial

C. Levinson, Brenna M. Williams, C. Christian, Rowan A. Hunt, Ani C. Keshishian, L. Brosof, Irina A. Vanzhula, Gabrielle Davis et al.

Journal of Consulting and Clinical Psychology, 2023

79 participants · 79 citations

Abstract

OBJECTIVE

Treatments for adults with eating disorders (EDs) only work in about 50% of individuals, and for some diagnoses (e.g., anorexia nervosa; atypical anorexia nervosa), there are no existing evidence-based treatments. Part of the reason that treatments may only work in a subset of individuals is because of the high heterogeneity present in the EDs, even within diagnoses. Manualized treatments delivered in a standard format may not always address the most relevant symptoms for a specific individual.

METHOD

The current open series trial recruited participants with transdiagnostic ED diagnoses (N = 79) to investigate the feasibility, acceptability, and initial clinical efficacy of a 10-session network-informed personalized treatment for eating disorders. This treatment uses idiographic (i.e., one-person) network models of ecological momentary assessment symptom data to match participants to evidence-based modules of treatment.

RESULTS

We found that network-informed personalized treatment was highly feasible with low dropout rates, was rated as highly acceptable, and had strong initial clinical efficacy. ED severity decreased from pre- to posttreatment and at 1-year follow-up with a large effect size. ED cognitions, behaviors, clinical impairment, worry, and depression also decreased from pre- to posttreatment.

CONCLUSIONS

These data suggest that network-informed personalized treatment has high acceptability and feasibility and can decrease ED and related pathology,…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 79 participants or records.

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