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Health Care Resource Utilization for Patients With Suspected Myocardial Infarction

Joseph Miller, B. Cook, S. Gunaga, R. Fadel, Chaun M. Gandolfo, Joshua Emakhu, Nick Mills, S. Mahler et al.

JAMA Network Open, 2025

32 participants · 4 citations

Abstract

Key Points Question Does implementing a 0-hour and 1-hour (hereafter referred to as 0/1-hour) high-sensitivity cardiac troponin I (hs-cTnI) protocol reduce health care resource utilization compared with a 0/3-hour standard protocol for myocardial infarction exclusion in US emergency departments (EDs)? Findings In a secondary analysis of this stepped-wedge randomized clinical trial including 32 608 patients with suspected myocardial infarction, a 0/1-hour hs-cTnI protocol reduced cardiac testing and the median length of ED stay without changing rates of ED discharge or revascularization. Meaning This study suggests that a 0/1-hour hs-cTnI protocol can reduce health care resource utilization and ED crowding without compromising safety.

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 32 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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