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Insights in altered eating behaviors in women with Ehlers-Danlos syndromes

Baeza-Velasco C, Tasa-Vinyals E, Espinoza P, Guillaume S, Mora MS, Bulbena A, Lorente S

Eating and weight disorders : EWD, 2026

121 participants

Abstract

Background: Recent research on Ehlers-Danlos syndromes (EDS) highlights a high frequency of disordered eating behaviors and Body Mass Index (BMI), especially in the hypermobile subtype. These problems might be secondary to EDS symptoms and comorbidities such as gastrointestinal (GI) problems, food allergies and oral pain, but also to psychological factors. To test this hypothesis, we explored the above-mentioned somatic and psychological features and their connexions with eating behavioural outcomes and BMI.

Method: Women with self-reported EDS (n = 121) completed an online survey assessing GI problems, food allergies, oral pain, somatosensory amplification, painful and fearful eating, eating avoidance and restriction, body satisfaction, and BMI. Path Analysis model was performed to examine the relationships among the variables.

Results: Significant relationships between GI problems and food allergies (B = 2.36, p = 0.035), fearful eating (B = 0.10, p = 0.043), painful eating (B = 0.02, p = 0.001) and somatosensory amplification (B = 1.01, p < 0.001) were observed. Also, positive relationships between painful and fearful eating (B = 0.76, p < 0.001), and fearful and avoidant eating (B = 0.78, p < 0.001).

Conclusions: These results support the idea that certain somatic symptoms common in EDS would lead to fear and avoidant responses to food. Further research is needed to better understand the link and directionality between abnormal connective tissue and disordered eating…

How strong is the evidence?

Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 121 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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