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Navigating the Aortopathy Dilemma in Pregnancy: Case Series Insights From a Cardiac Surgical Center

Fairley SL, Tromop-van Dalen C, Kirby A, Aitken A, Lodge JS, Gunderson S, Bowden V, Galvin S et al.

JACC. Case reports, 2026

Abstract

Aortic dissection during pregnancy most commonly occurs in women with undiagnosed aortopathies. High-risk aortopathies can be managed successfully throughout pregnancy within a pregnancy heart team model of care. The 2025 European Society of Cardiology guidelines provide comprehensive recommendations on the management of cardiac disease during pregnancy. We describe 4 cases of high-risk and very-high risk aortopathies that were successfully managed through pregnancy, including 1 patient with bicuspid aortic valve aortopathy who underwent successful cardiac surgery in the early second trimester. Pregnancy should no longer be a barrier to gold-standard or guideline-directed care for our high-risk cardiac patients.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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