Commentary on “Sacroiliac joint fusion in patients with Ehlers Danlos syndrome: A case series”
Abstract
Ehlers Danlos syndrome (EDS) is a genetic condition that affects con-nective tissue and can lead to a wide range of symptoms, including chronic pain and instability of the spine/related joints. The reviewed study by Beijk [1] retrospectively evaluated a continuous case series of patients who underwent Sacroiliac (SI) joint fusion for SI joint dysfunc-tion in patients with EDS. This study is unique as there have been few studies on the orthopaedic management of patients with EDS and no studies specific on SI joint fusions for this patient population. Patients with genetically or clinically diagnosed EDS who had under-gone SI joint fusion at a single institution over a period of 7 years (Jan-uary 2012– December 2018) with a mean follow up of 36 months were included in the study. The patients’ pain and functional outcomes were evaluated with questionnaire (satisfaction performance scale- 0– 100 points), and clinical data, along with imaging details, were extracted from their files. The intraoperative fluoroscopy and postoperative CT scans were conducted to assess adequate positioning of the implants In total, 16 patients were included in the study of which 14 underwent bilateral fusion of the SI joints and two underwent unilateral fusions, resulting in a total of 30 SI joint fusions. All of them were female, the median age was 46 years and the mean BMI was 23.3 kg/m 2 . Before the surgery, 15 of the 16 patients received diagnostic lidocaine injec-tions, which resulted in significant…
Read the paper
Related studies
- The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices
- The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities
- In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling
- In silico prediction of splice-altering single nucleotide variants in the human genome
- In silico clinical trials: how computer simulation will transform the biomedical industry
- In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.