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Management of Febrile Infants in a Rural Hospital: Comparison to Clinical Guidelines

N. Teng, J. Preddy

The Australian journal of rural health, 2025

Abstract

OBJECTIVE

Primary: To evaluate adherence to statewide guidelines for managing fever in infants < 90 days old presenting to rural hospital EDs in southern NSW. Comparisons were made between level 1-2 and level 4 rural hospitals. Secondary: To assess the utility of laboratory markers in differentiating bacterial from viral infections.

DESIGN

Retrospective observational study.

SETTING

Wagga Wagga Base Hospital, a regional centre in NSW, Australia.

PARTICIPANTS

One hundred thirty-four febrile children aged 0-90 days.

MAIN OUTCOME MEASURES

Adherence to guideline-recommended investigations (basic bloods, blood culture, urine culture, lumbar puncture) and management (antibiotics, time to antibiotics). Positive predictive values of CRP, white cell count (WCC) and neutrophil count for serious bacterial infections (SBIs) were calculated.

RESULTS

Guideline adherence: blood tests 79%, blood culture 79%, urine culture 76%, lumbar puncture 56% and parenteral antibiotics 83%. Adherence to blood/urine cultures was higher in the < 1 month age group than the 30-90 day age group. Investigations and management at level 1-2 hospitals were similar to the level 4 hospital, except regarding urine cultures in the < 1 month old age group. We observed higher CRP levels in infants diagnosed with SBIs compared to those without.

CONCLUSION

Management of febrile infants < 90 days in southern NSW rural hospitals aligns well with guidelines, except for lumbar punctures in infants < 1 month. Level 1-2…

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