Genome Resource Banking of Laboratory Animal Models
Abstract
J. K. Critser, Ph.D., is Director of the Cryobiology Institute and Professor in the Departments of Pediatrics and Immunology and Microbiology, Indiana University Medical School, Indianapolis, Indiana. Robert J. Russell, D.V.M., is Director of Laboratory Animal Medicine at Harlan Sprague Dawley, Inc., Indianapolis, Indiana. J. K. Critser, Ph.D., is Director of the Cryobiology Institute and Professor in the Departments of Pediatrics and Immunology and Microbiology, Indiana University Medical School, Indianapolis, Indiana. Robert J. Russell, D.V.M., is Director of Laboratory Animal Medicine at Harlan Sprague Dawley, Inc., Indianapolis, Indiana. “There can be no doubt that above all we, as a society and unified scientific community, must first understand the crucial need for genetic resource conservation. Given that, then the natural question becomes where do we go from here? The answer is to first identify needs and then logical priorities and strategies followed by implementation … There is a fundamental need to know what is out there, its character, its usefulness, and how to protect it” ( Wildt 1997 , p. 429–431). These concepts were stated in the broad context of identifying and preserving biodiversity. However, they apply equally well to the specific case of preserving genetic resources and related issues that are currently exploding in laboratory animal research. This concept of an “explosion” of increasing numbers of new genotypes of laboratory animals brings with it a…
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