Preventive dental erosion with silver diamine fluoride: an in vitro study
Abstract
OBJECTIVES
To evaluate the erosion preventive effect of 38% silver diamine fluoride (SDF) solution in enamel and dentin of human permanent teeth.
METHODS
Ninety enamel and ninety dentin blocks were prepared from permanent molars and allocated into three groups. Gp-SDF received a one-off application of 38% SDF solution. Gp-SNF received a one-off application of a solution containing 800ppm stannous chloride and 500ppm fluoride. Gp-DW received a one-off application of deionized water. The blocks were submitted to acid challenge at pH 3.2, 2 minutes, 5 times/day for 7 days. All blocks were immersed in human saliva between cycles for one hour. The crystal characteristics, percentage of surface microhardness loss (%SMHL), surface loss, and elemental analysis and surface morphology were examined by X-ray diffraction (XRD), microhardness test, non-contact profilometry, and energy-dispersive X-ray spectroscopy (EDS) and scanning electron microscopy (SEM), respectively. Data of %SMHL and surface loss were analyzed by one-way ANOVA.
RESULTS
XRD spectra revealed that fluorapatite and silver compounds formed in Gp-SDF, while fluorapatite and stannous compounds formed in Gp-SNF. Gp-DW presented only hydroxyapatite. The median (interquartile range) of %SMHL in Gp-SDF, Gp-SNF and Gp-DW were 27.86(3.66), 43.41(2.45), and 46.40(3.54) in enamel (p<0.001), and 14.21(1.57), 27.99(1.95), and 33.18(1.73) in dentin, respectively (p<0.001). The mean (standard deviation, μm) of surface loss of…
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