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In-vitro antidiabetic, antioxidant, antimicrobial and cytotoxic activity of Murraya koenigii leaf extract Intercedes ZnO nanoparticles

Avinash Sharma, R. Nagraik, Baskar Venkidasamy, Azhar Khan, K. Dulta, P. Chauhan, Deepak Kumar, Dong-Soo Shin

Luminescence (Chichester, England Print), 2022

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Abstract

Nanotechnology is an emerging field with tremendous potential andusage of medicinal plants and green preparation of nanoparticles is one of the widely explored areas. These have shown to be effective against different biological activities like diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc nanoparticles (ZnONPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide nanoparticles (MK ZnONPs) were characterized by UV-Visible spectroscopy, dynamic light scattering (DLS), fourier transformed infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FESEM), energy-dispersive spectrum (EDS) and Cyclic Voltammetry (CV). The synthesized MK ZnONPs were evaluated for their in-vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity it demonstrated significant anti-diabetic and cytotoxic activity, as well as moderate free-radical scavenging and antibacterial activity.

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