Comparative evaluation of remineralizing potential of different commercially available remineralizing agents : an in vitro scanning electron microscopy/EDS study
Abstract
Background - Modern dentistry aims at non-invasive & biological approach using remineralizing agents for management of early carious lesion. Aim- To evaluate and compare the remineralizing potential of three commercially available remineralizing agents containing SDF(Fagamin), CPP-ACPF(GC Tooth Mousse Plus) and BiominF(Elsenz) on demineralized enamel. Material and methods- Samples from forty extracted premolar teeth were selected and subjected to demineralizing solution for 96 hrs to create white spot lesion. The demineralized samples were randomly allocated into four groups:Group I(control group), Group II(SDF),Group III(CPPACPF),Group IV(Elsenz). White spot lesion containing demineralized samples were subjected to the test agents for 5 minutes everyday for 30 days. Scanning electron microscope (SEM) and Energy dispersive Spectroscopy (EDS) analysis were carried out at pre-remineralization and post-remineralization stage. The data were analyzed using SPSS 19.0 software Statistical Analysis- with one-way ANOVA and paired t-test. Results- All three test agents showed signicant remineralization of previously demineralized lesions. However, Elsenz showed the greatest remineralization, followed by SDF and then CPP-ACPF paste. Elsenz proved to be Conclusion- the best remineralizing agent and can be strongly recommended as an alternative to other remineralizing agents used in this study.
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