The future of in silico chemical safety … and beyond
Abstract
This commentary offers some perspectives on the future of in silico chemical safety assessment, grouped into four main themes: science, technology, regulation, and culture. The commentary is based on a talk given by Dr Andrew Worth at a Symposium entitled “Navigating In Silico Chemical Safety” held at the Friedrich-Alexander-University (FAU) in Erlangen, Germany on 11 October 2018.
How strong is the evidence?
Evidence Hub reads this as a simulation / modelling, done in computer models (in silico), not in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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