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Prevalence, incidence, systemic, behavioral, and patient‐related risk factors and indicators for peri‐implant diseases: An AO/AAP systematic review and meta‐analysis

M. Galárraga-Vinueza, Sarah E. Pagni, Matthew D. Finkelman, Todd R. Schoenbaum, L. Chambrone

The Journal of Periodontology, 2025

13,030 participants · 55 citations

Abstract

Abstract Background A profound understanding of the epidemiology of peri‐implant diseases (PIDs) is essential for the development of preventive approaches to mitigate the occurrence and progression of peri‐implant biological complications. The present systematic review and meta‐analysis aimed to assess the incidence, prevalence, systemic, behavioral, and patient‐related risk indicators and factors for PIDs in adult patients with dental implants. Methods Clinical studies assessing the prevalence, incidence, systemic risk indicators, and risk factors for PIDs were considered eligible for inclusion. MEDLINE–PubMed, EMBASE, Cochrane Central Library, and ClinicalTrials.gov electronic databases were searched for published articles. Pooled data analyses were performed using random‐effects models to identify risk indicators and factors for PIDs. Results Of 1120 potentially eligible records, 102 studies met the eligibility criteria and were included in this systematic review. Prevalence rates at the patient level for peri‐implant mucositis and peri‐implantitis were 46% (95% confidence interval [CI], 41–51) and 21% (95% CI, 17–24), respectively. Weighted mean incidence rates at the patient level for peri‐implant mucositis and peri‐implantitis were 53% and 22%, respectively, within 20 years of function. Pooled estimates identified periodontitis, obesity, and smoking habits as significant systemic risk indicators for mucositis. For peri‐implantitis, the significant risk indicators were…

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Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 13,030 participants or records.

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