Empagliflozin role in the treatment of type 2 diabetes with cardiovascular disease and subclinical cardiovascular disease in outpatient setting: case reports
Abstract
SGLT2 inhibitors based on recent evidence have shown promising Cardio vascular benefits apart from Glycemic Control in T2DM management. ESC-EASD 2019 clearly suggest that All SGLT2i reduces CV risk (3P MACE), HHF, worsening of Nephropathy .Only Empagliflozin has been recommended for reducing the Risk of CV death in T2DM with ASCVD & the CV death remains independent of baseline HbA1c or control of HbA1c. Empagliflozin CV death is very unique because the consistency of Mortality benefit remains very significant in patients of T2DM with various CVD (like Single Vessel disease CAD, Multiple Vessel Disease CAD, Prior CABG, Prior MI, Prior Stroke, Prior HHF, PAD).
Read the paper
Related studies
- Strategy for Mitigating DKA Risk in Patients with Type 1 Diabetes on Adjunctive Treatment with SGLT Inhibitors: A STICH Protocol
- Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance
- SGLT2 Inhibitors in Heart Failure: Targeted Metabolomics and Energetic Metabolism
- Mechanisms of blood pressure reduction with sodium-glucose co-transporter 2 (SGLT2) inhibitors
- Sodium-glucose cotransporter inhibitors: beyond glycaemic control
- Decoding the effects of SGLT2 inhibitors on cardiac arrhythmias in heart failure
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.