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Individual and combined effects of chemical and mechanical power on postoperative pulmonary complications: a secondary analysis of the REPEAT study

L. M. Müller-Wirtz, T. Lilien, William M. Patterson, Sascha Ott, Roland C. E. Francis, Marcelo Gama de Abreu, Ary Serpa, R. Bem et al.

Anaesthesia, 2025

12 citations

Abstract

Intra‐operative supplemental oxygen and mechanical ventilation expose the lungs to potentially injurious energy. This can be quantified as ‘chemical power’ and ‘mechanical power’, respectively. In this study, we sought to determine if intra‐operative chemical and mechanical power, individually and/or in combination, are associated with postoperative pulmonary complications.

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Evidence Hub reads this as a secondary / pooled analysis. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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