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Incidence and Risk Factors of Peri‐Implantitis Over Time—A Prospective Cohort Study

M. Romandini, Cristina Lima, Diogo Banaco, Rita Azevedo, M. Sanz

Journal of Periodontal Research, 2025

73 participants · 28 citations

Abstract

ABSTRACT Aim This prospective cohort study aimed to evaluate the incidence and risk/protective factors of peri‐implantitis over time. Methods A university‐representative cohort was evaluated at baseline and after a mean follow‐up time of 3.9 years. The main outcome was the incidence of peri‐implantitis, defined as bone loss > 1 mm between the two examinations in implants showing bleeding on probing. Putative risk/protective factors assessed at baseline were tested through multilevel (mixed‐effects) logistic regression analyses. Results A total of 73 patients with 322 implants were included. During the follow‐up period, 14 implants (4.3%) were lost in 9 patients (12.3%). Incidence of peri‐implantitis was observed in 22.2% of patients and 9.4% of implants. In the final multilevel multiple logistic regression model, the following factors were associated with occurrence of peri‐implantitis: periodontitis severity (stage IV periodontitis: OR = 41.29; 95% CI: 4.10–415.54), periodontal bone loss/age ratio (> 1: OR = 8.87; 95% CI: 1.47–53.73), smoking (current smokers: OR = 7.84; 95% CI: 1.83–33.50), sleep duration (> 7 h: OR = 19.97; 95% CI: 1.69–236.39), implant location (incisor: OR = 60.60; 95% CI: 4.04–908.33), restoration type (full‐arch fixed restorations: OR = 89.84; 95% CI: 3.66–2202.97), and restoration margin location (juxta‐marginal: OR = 14.17; 95% CI: 1.20–166.76). Keratinized tissue width assessed at baseline was not associated with incidence of peri‐implantitis.…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 73 participants or records.

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