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Risk factor analysis and etiological pathogen spectrum for urinary tract infection in children

T. Sorokman, M. G. Gingulyak, O. Makarova, N. Popeliuk

Zaporozhye Medical Journal, 2025

238 participants

Abstract

The problem of urinary tract infection (UTI) in children remains relevant in modern pediatrics, pediatric nephrology, and urology, despite the large number of works focused on this issue studies.

Aim. To analyze the potential predictors of development and examine the etiological spectrum of pathogens for urinary tract infection in children.

Materials and methods. Medical documentation of 238 children aged 1 to 14 years was analyzed. Children were divided into two groups: I – children with UTI (n = 140), II – children without UTI (n = 98). The patient group inclusion criteria for children with UTI met the recommendations of the European Society of Pediatric Urology. Urine culture for microbial flora and antibiotic sensitivity were performed according to standard methods.

Results. UTIs occurred in 32.7 % of boys and 26.1 % of girls. The most frequent UTIs were registered in the 1–3 years age group (54.3 %). Sex-specifics of UTIs were noted, varying depending on age: at the age of 1–3 years, girls were 1.3 times more likely to have UTIs than boys (95 % CI: 0.8–2.5); at the age of 4–7 years, boys were 1.4 times more likely to have UTIs (95 % CI: 0.9–3.4) than girls. Most common in children were vesicoureteral reflux (passive 34.5 % and active 19.2 %), cryptorchidism (12.1 %), and pyelectasia (10.3 %). According to the results of questioning, a positive family history of nephro-urological diseases was found in 35.7 % of patients. Age, heredity, neurogenic bladder, duration and…

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