Pediatric ricin toxicity from castor seed ingestion: a case report from Nepal
Abstract
Introduction: The castor oil plant (Ricinus communis), which is widely used in traditional medicine, contains ricin, a highly toxic ribosome-inactivating protein. The accidental ingestion of castor seeds poses significant health risks, particularly in the pediatric population.
Case presentation: We report a case of ricin toxicity in a 6-year-old boy following castor seed ingestion in Nepal. The patient presented with gastrointestinal symptoms, which necessitated prompt evaluation and supportive management in a resource-limited setting.
Discussion: This case illustrates the diagnostic dilemma of plant toxin ingestion in children, the effectiveness of basic supportive care despite the absence of specific antidotes, and the emerging role of rapid diagnostic tools in facilitating early detection and resolving the diagnostic uncertainty.
Conclusion: This case demonstrates the risks of ricin poisoning in children and emphasizes the need for greater public awareness and improved healthcare preparedness in regions where castor oil plants are endemic.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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