Clinical Perspective on Midgut Nonrotation in Adults: A Clinical Case Report and Review of the Literature
Abstract
Objective: To present a case of intestinal nonrotation in a 26-year-old Indian male and conduct a detailed review of 16 additional cases from the PubMed database.
Case presentation: A 26-year-old male presented with acute right lower quadrant abdominal pain and vomiting. He had a similar episode seven years prior that self-resolved. Physical examination revealed generalized abdominal tenderness, guarding, and mild distention. Imaging studies, including abdominal ultrasound and CECT, confirmed midgut volvulus due to nonrotation. The patient underwent exploratory laparotomy and Ladd's procedure, leading to an uneventful recovery and discharge on postoperative day seven.
Material and methods: A comprehensive PubMed search was conducted for case reports on midgut nonrotation in adults. 15 relevant cases were selected, and including the present case, 16 cases were reviewed.
Results: The mean age at presentation was 55.19 years (range: 26-86), with a slight male predominance (56.2%). The most common symptoms were acute abdominal pain (50%) and vomiting (31.25%). Notably, 50% of cases were identified incidentally during evaluations for unrelated conditions or procedures. CT scans confirmed diagnoses in 87.5% of cases. Positional anomalies included right-sided small bowel and left-sided colon in 37.5% and reversed SMA/SMV relationships in 33%. Ladd's procedure was performed in 25% of cases.
Conclusion: Midgut nonrotation, resulting from abnormal embryonic bowel rotation, can occur…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Patient-Centered Pharmaceutical Design to Improve Acceptability of Medicines: Similarities and Differences in Paediatric and Geriatric Populations
- Evidence-based clinical practice guidelines for irritable bowel syndrome 2020
- Phase 2b Study of Pimodivir (JNJ-63623872) as Monotherapy or in Combination With Oseltamivir for Treatment of Acute Uncomplicated Seasonal Influenza A: TOPAZ Trial
- Gastrointestinal manifestations in COVID-19
- COVID-19 and Gastrointestinal Disease: Implications for the Gastroenterologist
- Persistent gut barrier damage and commensal bacterial influx following eradication of Giardia infection in mice
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.