Is it useful at-home administration of ondansetron after an emergency visit in children with gastroenteritis?
Abstract
Authors´ conclusions: among children with gastroenteritis-associated vomiting, the provision of ondansetron after a pediatric emergency department visit led to lower risk of moderate-to-severe gastroenteritis during the subsequent 7 days compared with placebo.
Reviewers´ commentary: despite a well-designed and methodologically sound study, the results of home ondansetron in cases of acute gastroenteritis have not demonstrated a clinically relevant impact sufficient to warrant changes in our current therapeutic practice.
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