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Evaluate the effectiveness of ondansetron in treating the vommiting for children < 5 years OLD with acute gastroenteritis at pediatrics department, HUE central hospital

Thi Cu Nguyen, Dinh Thai Uong

Journal of Medicine and Pharmacy, 2011

86 participants

Abstract

Background: To control the vommit symptom give more successful and easier to oral fluid infusion, reduce the cost and work if using IV infusion. All over the world there are many studies on using Ondansetron for vommint preventing in gastroenteritis in children and show the effectiveness and safety. At Hue, Ondansetron mainly use for vommit preventing for children patients treated by chemotherapy and radiotherapy. There was no study about using Ondansetron to vommit preventing and treating for children patients with acute gastroenteritis. The aim of this study is to evaluate the effectiveness of Ondansetron in vommit treating for children with acute gastroenteritis. Population and study methods: children from 6 mths to 5yrs with acute gastroenteritis at Pediatric department of Hue Central Hospital. Using the method of clinical intervention with control group. 2 groups had the similarity of age, gender, onset duration of vommit, dehydration situation. Sample size: 86 children in control group and 41 children for study group. Study group with intervention) : only one shoot Ondansetron 0,2mg/kg + treatment plan fordedration + Zinc suppement as IMCI guidelines. Control group: treating by treatment plan for dehydration + Zinc suppement as IMCI guidelines. Both two groups will follow up about the situation of vommit, watery stools and the amount of ORS, the amount of IV fluid. Result: The rate of patient without vommit in the time from intervention to hospital discharge: Group…

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