Indirect Effects of Universal Infant Rotavirus Vaccination: A Narrative Systematic Review
Abstract
Background/Objective: Rotavirus is a major cause of acute gastroenteritis (AGE) in children 18 years). Results: From an initial 757 articles, 44 studies including 9,327,974 participants were included. In unvaccinated children 18 years. Indirect effects appeared to be greater in higher income and lower under-five mortality settings. Conclusions: Understanding these indirect benefits is crucial for evaluating the broader impact and cost-effectiveness of rotavirus immunisation programs.
How strong is the evidence?
Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 9,327,974 participants or records.
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